Pre-conference workshop:
Platform trials and master protocols
Presented by our visiting international guests Thomas Jaki and James Wason, our full day pre-conference workshop on adaptive trials is open to all.
Master protocols are a class of efficient clinical trial designs that seek to answer multiple research questions within a single trial protocol and include platform, basket and umbrella trials. The advantages of using such designs are many, ranging from use of a shared trial infrastructure to reusing information within the study (e.g. using a single control group or borrowing of information).
In this course we provide an overview of statistical approaches to the design and analysis of Master protocols in a mixture of lectures and practical sessions. The following topics will be discussed:
· A framework for designing multi-arm multi-stage platform trials
· Methods for information borrowing with application to Basket and Umbrella trials
· Software for Master protocols
· Practical considerations when implementing a Master protocol
Tutors
Professor Thomas Jaki - Professor of Statistics at University of Regensburg and Professor of Statistics at University of Cambridge
Professor James Wason – Professor of Biostatistics at Newcastle University
Practicals
Course delegates should bring their own laptops with R installed for the practical sessions. Although some experience with R would be an advantage, code will be given. Some practical questions will use Shiny apps, which won’t require R.
Schedule
Time (AEDT) Topic
10:00-10:05 Introductions
10:05-11:00 Lecture 1 – Multi-arm multi-stage designs
11:00-11:30 Morning tea break
11:30-12:15 Lecture 2 – Platform trials
12:15-13:00 Practical 1
13:00 – 14:00 Lunch break
14:00-14:45 Lecture 3 – Basket and umbrella trials
14:45-15:30 Lecture 4 - Information borrowing methods for basket and umbrella trials
15:30-16:00 Tea break
16:00-16:45 Practical 2
16:45-17:15 Lecture 5 – Discussion, regulation, and practical issues
Monday 16th October, 10am-5:15pm AEDT
Ground Floor lecture theatres
Monash University School of Public Health and Preventive Medicine
553 St Kilda Road, Melbourne 3004
And online via Zoom
Ticket prices
NB. All prices are listed in Australian Dollars inclusive of GST (10% of the sale price).
Delegates accessing the conference from outside Australia (i.e. online only) will not have GST applied to their ticket.
We are pleased to offer a small discount when purchasing your conference ticket in conjunction with the pre-conference workshop.
Standard conference PLUS pre-conference workshop $1000
Student conference PLUS pre-conference workshop $500
Standard pre-conference workshop only $400
Student pre-conference workshop only $200
Refunds and exchanges:
Delegates wishing to return, exchange, or switch their ticket type must request this by email to austrim@monash.edu no later than 1 September 2023. We are unable to accommodate extra in-person delegates on the day.
Delegates who are experiencing any respiratory symptoms on the day of the event are requested to not attend in person.
You will be provided with the details to join online in advance of the event.